Reply: genetic polymorphisms and cerebrovascular disease in children with sickle cell anemia from Rio de Janeiro, Brazil.
نویسندگان
چکیده
1BSc, MSc, PhD, Instituto de Pesquisa Clínica Evandro Chagas, Fundação Oswaldo Cruz, Rio de Janeiro RJ, Brasil; 2MD, MSc, PhD, Instituto de Pesquisa Clínica Evandro Chagas, Fundação Oswaldo Cruz, Rio de Janeiro RJ, Brasil; 3 MD, PhD, Instituto de Pesquisa Clínica Evandro Chagas, Fundação Oswaldo Cruz, Rio de Janeiro RJ, Brasil; 4MD, MSc, PhD, Instituto Estadual de Hematologia Arthur de Siqueira Cavalcante, Rio de Janeiro RJ, Brasil; 5MD, Instituto Estadual de Hematologia Arthur de Siqueira Cavalcante, Rio de Janeiro, Brasil; 6MD, MSc, PhD, Universidade Federal Fluminense, Niterói RJ, Brasil. Correspondence: Isaac Lima da Silva Filho; Laboratório de Pesquisa em Patogenia Viral, Instituto de Pesquisa Clínica Evandro Chagas, Fundação Oswaldo Cruz; Avenida Brasil 4365; 21045-900 Rio de Janeiro RJ Brasil; E-mail: [email protected] Conflict of interest: There is no conflict of interest to declare. Received 29 March 2012; Accepted 05 April 2012.
منابع مشابه
Genetic polymorphisms and cerebrovascular disease in children with sickle cell anemia from Rio de Janeiro, Brazil.
The aim of the present work was to examine possible genetic risk factors related to the occurrence of cerebrovascular disease (CVD) in Brazilian population, the frequency of β(S)-globin gene haplotypes and co-inheritance with α-thalassemia (-α(3.7kb)) and single nucleotide polymorphism of methylenetetrahydrofolate reductase (MTHFR-C677T), Factor V Leiden (FV-G1691A) and prothrombin (PT-G20210A)...
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متن کاملSickle cell disease: acute clinical manifestations in early childhood and molecular characteristics in a group of children in Rio de Janeiro
OBJECTIVES To describe clinical events of sickle cell disease and the correlation with β-globin haplotypes and α-thalassemia in under 6-year-old children. METHODS A retrospective study was conducted of under 6-year-old children from the neonatal screening program in Rio de Janeiro. Forty-eight male and 48 female children were enrolled in this study, 79 with sickle cell anemia and 17 with hemo...
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ورودعنوان ژورنال:
- Arquivos de neuro-psiquiatria
دوره 70 8 شماره
صفحات -
تاریخ انتشار 2012